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The estimated glomerular filtration rate (eGFR) is a measure of kidney function. [6] Adding a race adjustment to kidney algorithms results in higher eGFR values in people identified as black. [7] [8] [9] Reasons for this vary, but it is thought to partially stem from the notion that Black persons are more muscular. [8]
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).
A glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m 2 is considered normal without chronic kidney disease if there is no kidney damage present. Kidney damage is defined signs of damage seen in blood, urine, or imaging studies which includes lab albumin/creatinine ratio (ACR) ≥ 30. [ 59 ]
The one-drop rule was a legal principle of racial classification that was prominent in the 20th-century United States. It asserted that any person with even one ancestor of African ancestry ("one drop" of "black blood") [1] [2] is considered black (Negro or colored in historical terms).
EGFR may refer to: Epidermal growth factor receptor (EGFR), a transmembrane receptor protein in humans Estimated glomerular filtration rate (eGFR), a measure of renal function
Mutations that lead to EGFR overexpression (known as upregulation or amplification) have been associated with a number of cancers, including adenocarcinoma of the lung (40% of cases), anal cancers, [18] glioblastoma (50%) and epithelian tumors of the head and neck (80–100%). [19]
In less than one generation, the average weight of a child has risen by 5 kg in the United States. [77] The CDC has reported that, in 2014, 17.2% of youth aged 2–19 were considered obese and another 16.2% were overweight. [78] Meaning, over one-third of children and teens in the US were overweight or obese.
However, its accuracy declines at the extremes of body fat percentages, tending to slightly understate the percent body fat in overweight and obese persons (by 1.68–2.94% depending on the method of calculation), and to overstate to a much larger degree the percent body fat in very lean subjects (by an average of 6.8%, with up to a 13% ...