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Micrograph showing apocrine metaplasia of the breast with typical features, [4] including apical snouts with eosinophilic granules. H&E stain. Apocrine metaplasia is a reversible transformation of cells to an apocrine phenotype. It is common in the breast in the context of fibrocystic change. It is seen in women mostly over the age of 50 years.
Micrograph showing apocrine metaplasia of the breast with typical features [3] H&E stain. Barrett's esophagus is an abnormal change in the cells of the lower esophagus, thought to be caused by damage from chronic stomach acid exposure. The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the ...
Micrograph showing apocrine-type metaplasia of the breast with typical oncocytes. [2] H&E stain. Oncocytes (left of image), as seen in a renal oncocytoma. H&E stain. An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.
The mammary gland is an apocrine gland. [2] Its lactiferous ducts have two layers of epithelial cells, a luminal layer which faces the duct's lumen (i.e. passageway) and a basal layer which lies beneath the luminal layer.
Apocrine metaplasia. Pathology Outlines. Last author update: 28 May 2020; Author: Mikael Häggström, M.D. Author info - Reusing images - Conflicts of interest:
Fibrocystic changes include fibroadenomas, fibrosis, papillomas of the breast, [1] and apocrine-type metaplasia. [4] Management may involve education about the condition, using a well fitting bra, and pain medication, if needed. [1] Occasionally danazol or tamoxifen may be used for pain. [1]
The goblet cells mainly use the merocrine method of secretion, secreting vesicles into a duct, but may use apocrine methods, budding off their secretions, when under stress. [2] The term goblet refers to the cell's goblet-like shape. The apical portion is shaped like a cup, as it is distended by abundant mucus laden granules; its basal portion ...
Epithelial cells come in a variety of shapes that relate to their function in development or physiology. How epithelial cells adopt particular shapes is poorly understood, but it must involve spatial control of the actin cytoskeleton, which is central to cell shape in all plant cells. Apocrine cells, showing apical snouts towards the lumen.