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Fentanyl is powerful synthetic opioid that can be up to 100 times more potent than morphine. ... About 5 out of every 10 fentanyl pills that the agency tested last year had lethal doses of the ...
To begin the certification process applicants must be a physician medical director at a long-term care facility, and have completed a post-graduate training program accredited by the U.S. Accreditation Council for Graduate Medical Education or American Osteopathic Association, or a Canadian Royal College of Physicians and Surgeons or College of ...
MDCalc was founded by two emergency physicians, Graham Walker, MD, and Joseph Habboushe, MD, MBA, [5] and provides over 500 medical calculators and other clinical decision-support tools. [6] The MDCalc.com website was launched in 2005. [5] In 2016, MDCalc launched an iOS app, [7] followed by an Android app in 2017. [8]
Hydrocodone is a highly selective full agonist of the μ-opioid receptor (MOR). [28] [54] [49] This is the main biological target of the endogenous opioid neuropeptide β-endorphin. [55] Hydrocodone has low affinity for the δ-opioid receptor (DOR) and the κ-opioid receptor (KOR), where it is an agonist similarly. [49]
The Anti-Drug Abuse Act of 1988, which created the Office of National Drug Control Policy, was the product of bi-partisan support.It was co-sponsored in the House of Representatives by parties' leaders, Tom Foley and Robert Michel, [5] and it passed by margins of 346–11 and 87–3 in the House and Senate, respectively. [6]
Publicis, a French marketing company, agreed to pay $350 million within the next two months and will not take on any more opioid clients, according to New York Attorney General Letitia James.
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
The opioid crisis contributed to more than 500,000 deaths in the U.S. in two decades. At the epicenter — three major pharmaceutical distributors and manufacturer Johnson & Johnson.