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GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both cholera toxin and E. coli heat-labile enterotoxin ( Traveller's diarrhea ).
The GM1 gangliosidoses, usually shortened to GM1, are gangliosidoses caused by mutation in the GLB1 gene resulting in a deficiency of beta-galactosidase.The deficiency causes abnormal storage of acidic lipid materials in cells of the central and peripheral nervous systems, but particularly in the nerve cells, resulting in progressive neurodegeneration.
Structure of GM1 ganglioside. A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. N-acetylneuraminic acid, NANA) linked on the sugar chain.
Levels of anti-GM1 antibodies are especially elevated in patients with prodromal diarrhea. [7] Titers to GM1 in other diseases (rheumatoid arthritis, primary Sjögren's syndrome and systemic lupus erythematosus) was also elevated. [8] Additionally highly significant association was found with rheumatoid arthritis and peripheral neuropathies. [9]
GM-1 (Göring Mischung 1) was a system for injecting nitrous oxide into aircraft engines that was used by the Luftwaffe in World War II.This increased the amount of oxygen in the fuel mixture, and thereby improved high-altitude performance.
This article needs editing to comply with Wikipedia's Manual of Style. In particular, it has problems with not using MEDMOS. ... GM1 gangliosidoses - GM1; GM2 ...
The Panasonic Lumix DMC-GM1 was announced October 2013, as Panasonic's "pocketable", Micro Four Thirds compact mirrorless interchangeable lens camera. It features the same sensor as the GX7 , AF detection range of -4 - 18 EV, focus peaking mode, an electronic shutter with speeds ranging from 60 - 1/16,000 sec, and Wi-Fi connectivity.
Structures of GM1, GM2, GM3 gangliosides. GM3 (monosialodihexosylganglioside) is a type of ganglioside. The letter G refers to ganglioside, and M is for monosialic acid as it has only one sialic acid group. The numbering is based on its relative mobility in electrophoresis among other monosialic gangliosides. [1]