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There is no universally recognized reference value range for DLCO as of 2017, [10] but values in the 80%-120% of predicted range based on instrument manufacturer standards are generally considered normal. [11] A D LCO of less than 60% predicted portends a poor prognosis for lung cancer resection.
Diffusing capacity of the lung (D L) (also known as transfer factor) measures the transfer of gas from air in the lung, to the red blood cells in lung blood vessels. It is part of a comprehensive series of pulmonary function tests to determine the overall ability of the lung to transport gas into and out of the blood.
Diffusing capacity (or DLCO) is the carbon monoxide uptake from a single inspiration in a standard time (usually 10 seconds). During the test the person inhales a test gas mixture that consisting of regular air that includes an inert tracer gas and CO, less than one percent.
Pulmonary function testing is a diagnostic and management tool used for a variety of reasons, such as: Diagnose lung disease. Monitor the effect of chronic diseases like asthma, chronic obstructive lung disease, or cystic fibrosis.
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Lomustine can cause or worsen pulmonary infiltrates and fibrosis in patients. Pulmonary toxicity generally occurs after at least 6 months of treatment with lumostine. Lung function should be monitored via Forced Vital Capacity (FVC) or Carbon Monoxide Diffusing Capacity (DLCO) tests to determine patients risk of developing pulmonary toxicities.
National Aerospace Standards (NAS) are U.S. industry standards for the aerospace industry. They are created and maintained by the Aerospace Industries Association (AIA). [ 1 ] The Federal Aviation Administration recognizes National Aerospace Standards as "traditional standards" for the purposes of parts approval.