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Mometasone/formoterol, sold under the brand name Dulera among others, is a fixed-dose combination medication used in the long-term treatment of asthma. [1] It contains mometasone a steroid and formoterol a long-acting beta agonist. [1] It is only recommended in those for whom an inhaled steroid is not sufficient. [1] It is used by inhalation. [1]
It contains budesonide, a steroid; and formoterol, a long-acting β 2-agonist (LABA). [2] The product monograph does not support its use for sudden worsening or treatment of active bronchospasm. [2] However, a 2020 review of the literature does support such use. [6] It is used by breathing in the medication. [2]
Formoterol, also known as eformoterol, is a long-acting β 2 agonist (LABA) used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). Formoterol has an extended duration of action (up to 12 h) compared to short-acting β 2 agonists such as salbutamol (albuterol), which are effective for 4 h to 6 h.
vilanterol is the ultra-LABA not available by itself but only as a component of combination drugs: with fluticasone furoate: Breo Ellipta , Relvar Ellipta (EU, RU). This second medication in this combination is the synthetic inhaled corticosteroid fluticasone furoate.
Fluticasone, a corticosteroid, works by decreasing inflammation while salmeterol, a long-acting beta-adrenoceptor agonist (LABA), works by activating beta-2 adrenergic receptors. [5] The combination was approved for medical use in the United States in 2000. [5] A generic version was approved in the United States in 2019. [7]
[6] [7] The medications work in different ways: fluticasone furoate is an inhaled corticosteroid (ICS), umeclidinium is a long-acting muscarinic antagonist (LAMA), and vilanterol is a long-acting beta-agonist (LABA). In 2022, it was the 144th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [8] [9]
Tiotropium bromide, sold under the brand name Spiriva among others, is a long-acting bronchodilator (LAMA: long acting muscarinic antagonist) used in the management of chronic obstructive pulmonary disease (COPD) and asthma.
The Laba (Russian: Лаба; Circassian: Лабэжъ Labez̄) is a river in Krasnodar Krai and Adygea of European Russia. It is a left tributary of the Kuban , which it joins at Ust-Labinsk . It is formed by the confluence of the Bolshaya Laba and the Malaya Laba (Малая Лаба; Лабэжьый Labez̄yj ).