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Most diethyl ether is produced as a byproduct of the vapor-phase hydration of ethylene to make ethanol.This process uses solid-supported phosphoric acid catalysts and can be adjusted to make more ether if the need arises: [9] Vapor-phase dehydration of ethanol over some alumina catalysts can give diethyl ether yields of up to 95%.
On 30 September 1846, Morton administered diethyl ether to Eben Frost, a music teacher from Boston, for a dental extraction. Two weeks later, Morton became the first to publicly demonstrate the use of diethyl ether as a general anesthetic at Massachusetts General Hospital, in what is known today as the Ether Dome. [105]
Drinking ether is challenging as it boils below body temperature and is not miscible with water, requiring precautions: . There is an art in swallowing the ether. The drinker first washes out his mouth with water “to cool it;” next he swallows a little water to cool his throat; then he tosses down the glass of ether; finally, he closes in with another draught of water to keep the ether ...
Inhaled agents like diethyl ether are critical in anesthesia. Diethyl ether initially replaced non-flammable (but more toxic) halogenated hydrocarbons like chloroform and trichloroethylene. Halothane is a halogenated hydrocarbon anesthetic agent that was introduced into clinical practice in 1956. Due to its ease of use and improved safety ...
A water miscible solvent often found in lithium batteries (b.p. 85 °C): Dioxane: A cyclic ether and high-boiling solvent (b.p. 101.1 °C). Tetrahydrofuran (THF) A cyclic ether, one of the most polar simple ethers that is used as a solvent. Anisole (methoxybenzene) An aryl ether and a major constituent of the essential oil of anise seed. Crown ...
Another water molecule comes along and takes up the extra proton. This reaction tends to yield many undesirable side products, (for example diethyl ether in the process of creating ethanol) and in its simple form described here is not considered very useful for the production of alcohol. Two approaches are taken.
Diethyl ether has a long history as a medical anesthetic; when starting fluid was mostly ether, a similar effect could be obtained using it. Use at the present time directly as an inhalant includes the effect of the petroleum solvents, which are more toxic as inhalants than diethyl ether. [7] [8]
The most widely used industrial process involves the acid-catalyzed dehydration of 1,4-butanediol. Ashland/ISP is one of the biggest producers of this chemical route. The method is similar to the production of diethyl ether from ethanol. The butanediol is derived from condensation of acetylene with formaldehyde followed by hydrogenation. [8]