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Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure.
For people with a life-shortening or terminal illness, such as a dementia, it is important to consider when to discontinue medications used to prevent future serious events. The Medication Appropriateness Tool for Comorbid Health conditions during Dementia ( MATCH-D ) provides guidance for clinicians and consumers on how to manage medications.
Other medications can be used when stimulants are not an option. These include the alpha-2 agonists (clonidine and guanfacine), tricyclic antidepressants (desipramine and nortriptyline), and newer antidepressants (bupropion and venlafaxine). There have been case reports of tics worsening with bupropion.
Rebound hypertension, above pre-treatment level, was observed after clonidine, [15] and guanfacine [16] discontinuation. Continuous usage of topical decongestants (nasal sprays) can lead to constant nasal congestion, known as rhinitis medicamentosa.
Lofexidine, sold under the brand name Lucemyra among others, [1] is a medication historically used to treat high blood pressure; today, it is more commonly used to help with the physical symptoms of opioid withdrawal. [2]
8 Use of guanfacine as treatment in cases of hyperadrenergic PoTS. 1 comment. 9 TAAR1 activity. 1 comment. Toggle the table of contents. Talk ...
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Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist that is selective to the alpha-2 adrenergic receptor.Guanabenz is used as an antihypertensive drug used in the treatment of high blood pressure (hypertension).