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Endoscopic submucosal dissection (ESD) is an advanced surgical procedure using endoscopy to remove gastrointestinal tumors that have not entered the muscle layer. ESD may be done in the esophagus, stomach or colon. Application of endoscopic resection (ER) to gastrointestinal (GI) neoplasms is limited to lesions with no risk of nodal metastasis.
Endoscopic mucosal resection and submucosal dissection are also highly effective methods for resection or large, non-malignant colorectal polyps and superficially (stage T1a) invasive colorectal cancers. The largest study of endoscopic mucosal resection by the Australian Consortium included 1000 cases and long term surveillance. [2]
The non-lifting sign was first described in 1994 by Yoshiharu Uno and Akihiro Munakata of the Hirosaki University School of Medicine, Japan. [2]In 1999 the same team showed that the presence of a non-lifting sign correlated with the depth of invasion of the submucosa by early colorectal cancers that were being considered for endoscopic resection. [3]
An endoclip is a metallic mechanical device used in endoscopy in order to close two mucosal surfaces without the need for surgery and suturing. Its function is similar to a suture in gross surgical applications, as it is used to join together two disjointed surfaces, but, can be applied through the channel of an endoscope under direct visualization
Treatments for early-stage colon or colorectal cancer can include a polypectomy, or the removal of polyps during a colonoscopy, or endoscopic mucosal resection, which is the removal of larger ...
Forms of endoscopic therapy have been used for stage 0 and I disease: endoscopic mucosal resection (EMR) [70] and mucosal ablation using radiofrequency ablation, photodynamic therapy, Nd-YAG laser, or argon plasma coagulation. Laser therapy is the use of high-intensity light to destroy tumor cells while affecting only the treated area. This is ...
Proximal gastrectomy (PG) can be considered a viable alternative for upper third early gastric cancer (EGC) [86] Of the different surgical techniques, endoscopic mucosal resection (EMR) is a treatment for early gastric cancer (tumor only involves the mucosa) that was pioneered in Japan and is available in the United States at some centers. [6]
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