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In men with prostate cancer, bicalutamide monotherapy has been found to increase the likelihood of death due to causes other than prostate cancer. Bicalutamide has been found to cause unfavorable liver changes in around 3 to 11% of people, with such changes necessitating discontinuation in approximately 1%.
This inflammation can cause pain and stiffness [5] and is one of the most common causes of ankle problems. [7] In many types of arthritis, progressive joint degeneration in the joint occurs and smooth "buffered" cartilage is gradually lost, causing the bones rub against each other and wear, as well as the soft joint tissue.
Age. The risk of most causes of joint pain increases with age. This may be due to increased wear and stress on joints over time and a higher likelihood of other underlying medical conditions ...
Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. [1] Early on, there may be no symptoms. [1] Gradually joint pain may develop, which may limit the person's ability to move. [1] Complications may include collapse of the bone or nearby joint surface. [1]
Ankle pain is also present in patients who have high level entrapments. Inflammation or swelling can occur within this tunnel for a number of reasons. The flexor retinaculum has a limited ability to stretch, so increased pressure will eventually cause compression on the nerve within the tunnel.
A magnesium deficiency may cause chondrocalcinosis, and there is anecdotal evidence that magnesium supplementation may reduce or alleviate symptoms. [7] In some cases, arthritis from injury can cause chondrocalcinosis. [8] Other causes of chondrocalcinosis include: [4] Hypercalcaemia, especially when caused by hyperparathyroidism; Arthritis ...
Hypertrophic osteoarthropathy is one of many distant effect disorders due to cancer, with lung cancer being the most common cause but also occurring with ovarian or adrenal malignancies. A distant effect disorder, or a paraneoplastic syndrome , affects distant areas and thus is not related to local compression or obstruction effects from the tumor.
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