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2. Abiraterone acetate - Wikipedia

   en.wikipedia.org/wiki/Abiraterone_acetate

   Abiraterone acetate, sold under the brand name Zytiga among others, is a medication used to treat prostate cancer. [10] Specifically it is used together with a corticosteroid for metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC).

3. Niraparib/abiraterone acetate - Wikipedia

   en.wikipedia.org/wiki/Niraparib/abiraterone_acetate

   It is used in combination with prednisolone or another medicine prednisone, which is converted into prednisolone. [2] In the United States, niraparib/abiraterone is indicated, in combination with prednisone, for adults with deleterious or suspected deleterious BRCA-mutated castration-resistant prostate cancer, as determined by an FDA-approved test.

4. Prednisone - Wikipedia

   en.wikipedia.org/wiki/Prednisone

   Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]

5. J&J's Prostate Cancer Drug Zytiga Approved for Earlier ... - AOL

   www.aol.com/news/2013-01-11-jjs-prostate-cancer...

   On Friday, Johnson & Johnson's Zytiga received an expanded approval from the European Commission. The drug was previously approved for patients with metastatic castration-resistant prostate cancer ...

6. The Terrible—and Amazing—Side Effects of Weight-Loss Drugs

   www.aol.com/terrible-amazing-side-effects-weight...

   GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now. GLP-1s ...

7. Corticosteroid - Wikipedia

   en.wikipedia.org/wiki/Corticosteroid

   Synthetic pharmaceutical drugs with corticosteroid-like effects are used in a variety of conditions, ranging from hematological neoplasms [3] to brain tumors or skin diseases. Dexamethasone and its derivatives are almost pure glucocorticoids, while prednisone and its derivatives have some mineralocorticoid action in addition to the ...

8. Can Zytiga Build on a Historic 2012? - AOL

   www.aol.com/news/2013-02-19-can-zytiga-build-on...

   Johnson & Johnson may offer well-known personal-care products such as Listerine and Neutrogena, but it also boasts an impressive portfolio of market-leading therapeutic compounds. The health-care ...

9. Apparent mineralocorticoid excess syndrome - Wikipedia

   en.wikipedia.org/wiki/Apparent_mineralocorticoid...

   Cortisol at high concentrations can cross-react and activate the mineralocorticoid receptor due to the non-selectivity of the receptor, leading to aldosterone-like effects in the kidney. This is what causes the hypokalemia, hypertension, and hypernatremia associated with the syndrome. Patients often present with severe hypertension and end ...