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For the analysis of a suspected hematological malignancy, a complete blood count and blood film are essential, as malignant cells can show in characteristic ways on light microscopy. When there is lymphadenopathy, a biopsy from a lymph node is generally undertaken surgically.
Distinct from adult T-cell leukemia (in which T-cell lymphotropic virus Type I causes malignant maturation of T-cells), T-ALL is a precursor for lymphoid neoplasm. [6] Its clinical presentation most commonly includes infiltration of the central nervous system (CNS, i.e. brain and spinal cord), and is often associated with a mediastinal mass ...
Ischaemic fasciitis, previously termed atypical decubital fibroplasia or decubital ischemic fasciitis, was thought to be a non-neoplastic lesion and to occur only in the deep subcutaneous tissue at pressure points or bone prominences but more recently has been found to be a benign neoplasm that can occur in a wider range of tissue sites. [5] [6]
3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).
The word leukemia, which means 'white blood', is derived from the characteristic high white blood cell count that presents in most affected people before treatment. The high number of white blood cells is apparent when a blood sample is viewed under a microscope, with the extra white blood cells frequently being immature or dysfunctional. The ...
Aggressive NK-cell leukemia is a disease with an aggressive, systemic proliferation of natural killer cells (NK cells) and a rapidly declining clinical course. [ 1 ] [ 2 ] [ 3 ] It is also called aggressive NK-cell lymphoma .
Hematoxylin and eosin stains from different sections of a single diffuse intrinsic pontine glioma specimen, showing low-grade (top) and high-grade (bottom) areas.. In pathology, grading is a measure of the cell appearance in tumors and other neoplasms.
A diagnosis of CUP requires a clinical picture consistent with metastatic disease and one or more biopsy results inconsistent with a tumor cancer. CUP is found in about 3 to 5% of all people diagnosed with invasive cancer, [1] and carries a poor prognosis in most (80 to 85%) of those circumstances. The other 15 to 20% of patients, however, have ...