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  2. Bortezomib - Wikipedia

    en.wikipedia.org/wiki/Bortezomib

    Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. [4] This includes multiple myeloma in those who have and have not previously received treatment. [ 3 ]

  3. Proteasome inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proteasome_inhibitor

    Bortezomib (Velcade) was approved in 2003. This was the first proteasome inhibitor approved for use in the U.S. Its boron atom binds the catalytic site of the 26S proteasome. [20] Carfilzomib (Kyprolis) was approved by the FDA for relapsed and refractory multiple myeloma in 2012 . [21]

  4. Bortezomib/dexamethasone - Wikipedia

    en.wikipedia.org/wiki/Bortezomib/dexamethasone

    Bortezomib/dexamethasone is a combination drug against multiple myeloma. [1] When bortezomib is used by the trade name Velcade, the combination is called Vel/Dex (or Vel-Dex or Veldex ). Bortezomib is a proteasome inhibitor and dexamethasone is a corticosteroid .

  5. Effervescent tablet - Wikipedia

    en.wikipedia.org/wiki/Effervescent_tablet

    Effervescent or carbon tablets are tablets which are designed to dissolve in water and release carbon dioxide. The carbon dioxide is generated by a reaction of a compound containing bicarbonate, such as sodium bicarbonate or magnesium bicarbonate, with an acid such as citric acid or tartaric acid. Both compounds are present in the tablet in ...

  6. Orally disintegrating tablet - Wikipedia

    en.wikipedia.org/wiki/Orally_disintegrating_tablet

    Clonazepam ODT blister pack and tablet Etizest-1 MD (Etizest-brand 1mg-doskk etizolam mouth-dissolving (MD) blister pack and opened tablet. An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of over-the-counter (OTC) and prescription medications.

  7. Arsenic trioxide - Wikipedia

    en.wikipedia.org/wiki/Arsenic_trioxide

    Arsenic trioxide is indicated in combination with tretinoin for treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia whose acute promyelocytic leukemia is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression; and for induction of remission and consolidation in patients with acute promyelocytic leukemia who are refractory to, or ...

  8. Parachute (drugs) - Wikipedia

    en.wikipedia.org/wiki/Parachute_(drugs)

    Parachuting or bombing is a method of swallowing drugs by rolling or folding powdered or crushed drugs in a piece of edible paper to ingest while avoiding the unpleasant taste of the chemical. [1]

  9. Dactolisib - Wikipedia

    en.wikipedia.org/wiki/Dactolisib

    Dactolisib (codenamed NVP-BEZ235 and BEZ-235, also known as RTB101) is an imidazoquinoline derivative acting as a PI3K inhibitor. [1] It also inhibits mTOR. [2] It is being investigated as a possible cancer treatment.

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