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Human skull with evidence of trepanation found at Monte Albán in Oaxaca, Mexico.. Trepanation in Mesoamerica has been practised by a number of pre-Columbian cultures in the Mesoamerican region, dating from at least the mid-Preclassic era (ca. 1500 BCE), and continuing up to the late Postclassic, or ca. 1200 CE.
Detail from The Extraction of the Stone of Madness, a painting by Hieronymus Bosch depicting trepanation (c. 1488–1516). Trepanning, also known as trepanation, trephination, trephining or making a burr hole (the verb trepan derives from Old French from Medieval Latin trepanum from Greek trúpanon, literally "borer, auger"), [1] [2] is a surgical intervention in which a hole is drilled or ...
Cancers treatments may include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. chemotherapy before surgery). Some of these cancer therapies may produce treatment-related, or ...
In March 2011, investigators from Australia and several other countries published the results of the DECRA [5] trial in The New England Journal of Medicine.This was a randomized trial comparing decompressive craniectomy to best medical therapy run between 2002 and 2010 to assess the optimal management of patients with medically refractory ICP following diffuse non-penetrating head injury.
The first trepanning procedure consisted of different types of tools and techniques: at the beginning the only material that was available for use, it was a sharp and carved rock. The development of The Hippocratic Corpus, written in the fifth century B.C., is the first written source that can be found about trepanning. The aim of the procedure ...
Trousseau described several cases in which recurrent thrombosis was the presenting feature of visceral cancer, and his confidence in the utility of this connection led him to say, "So great, in my opinion, is the semiotic value of phlegmasia in the cancerous cachexia, that I regard this phlegmasia as a sign of the cancerous diathesis as certain ...
The Mayo Clinic Cancer Center is one of the oldest NCI-designated cancer centers in the United States, having first been designated in 1973. [3] The main location of the Mayo Clinic is in Rochester, MN. Campuses in Arizona and Florida opened later and became part of the Mayo Clinic Cancer Center in 2003. [4] [5]
The surgeries and complex treatment regimens used in cancer therapy have led the term to be used mainly to describe adjuvant cancer treatments. An example of such adjuvant therapy is the additional treatment [ 1 ] usually given after surgery where all detectable disease has been removed, but where there remains a statistical risk of relapse due ...