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Coxsackie A virus is a subgroup of enterovirus A, which are small, non-enveloped, positive-sense, single-stranded RNA viruses. Its protective, icosahedral capsid has an external portion that contains sixty copies of viral proteins (VP1,-2,-3) and an internal portion surrounding the RNA genome containing sixty copies of VP4 viral proteins.
Coxsackieviruses are divided into group A and group B viruses based on early observations of their pathogenicity in neonatal mice. [1] Group A coxsackieviruses were noted to cause a flaccid paralysis (which was caused by generalized myositis) while group B coxsackieviruses were noted to cause a spastic paralysis (due to focal muscle injury and degeneration of neuronal tissue).
The Coxsackie B viruses are also reported to cause a spastic paralysis due to the degeneration of neuronal tissue and muscle injury. Infections usually occur during warm summer months with symptoms including exanthema, pleurodynia, flu-like illness consisting of fever, fatigue, malaise, myalgia, nausea, abdominal pain and vomiting. [12]
“There are more than 200 types of cancer, with lots of possible symptoms,” says Dr Julie Sharp, head of health and patient information at CRUK. “It’s impossible to know them all, which is ...
As a poll finds half of adults with possible cancer symptoms don’t contact a doctor within 6 months
Coxsackievirus A16 is the most common cause, and enterovirus 71 is the second-most common cause. [6] Other strains of coxsackievirus and enterovirus can also be responsible. [6] [12] Some people may carry and pass on the virus despite having no symptoms of disease. [10] Other animals are not involved. [8] Diagnosis can often be made based on ...
Herpangina, also called mouth blisters, is a painful mouth infection caused by coxsackieviruses.Usually, herpangina is produced by one particular strain of coxsackie virus A (and the term "herpangina virus" refers to coxsackievirus A), [1] but it can also be caused by coxsackievirus B or echoviruses. [2]
Cases have risen dramatically over last decade, according to recent research