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Process Safety Management of Highly Hazardous Chemicals is a regulation promulgated by the U.S. Occupational Safety and Health Administration (OSHA). [1] It defines and regulates a process safety management (PSM) program for plants using, storing, manufacturing, handling or carrying out on-site movement of hazardous materials above defined amount thresholds.
Process safety management (PSM) is a practice to manage business operations critical to process safety. It can be implemented using the established OSHA scheme [1] or others made available by the EPA, [2] AIChE's Center for Chemical Process Safety, [3] or the Energy Institute. [4] PSM schemes are organized in 'elements'.
Process safety is an interdisciplinary engineering domain focusing on the study, prevention, and management of large-scale fires, explosions and chemical accidents (such as toxic gas clouds) in process plants or other facilities dealing with hazardous materials, such as refineries and oil and gas (onshore and offshore) production installations ...
A process hazard analysis (PHA) (or process hazard evaluation) is an exercise for the identification of hazards of a process facility and the qualitative or semi-quantitative assessment of the associated risk.
Manufacturing processes must be clearly defined and controlled. All critical processes are validated to ensure consistency and compliance with specifications. Manufacturing processes must be controlled, and any changes to the process must be evaluated. Changes that affect the quality of the drug are validated as necessary.
Protection through the use of safety layers. A process plant shutdown system is a functional safety countermeasure crucial in any hazardous process plant such as oil and gas production plants and oil refineries. The concept also applies to non-process facilities such as nuclear plants. These systems are used to protect people, assets, and the ...