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A tuberculoma is a clinical manifestation of tuberculosis which conglomerates tubercles into a firm lump, and so can mimic cancer tumors of many types in medical imaging studies. [1] [2] They often arise within individuals in whom a primary tuberculosis infection is not well controlled. [3]
Mycobacterium tuberculosis of the meninges is the cardinal feature and the inflammation is concentrated towards the base of the brain. [6] When the inflammation is in the brain stem subarachnoid area, cranial nerve roots may be affected. The symptoms will mimic those of space-occupying lesions. [7]
Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is known as latent tuberculosis . [ 1 ] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [ 1 ]
An infection in the neck area can cause nerve problems affecting both the arms and legs, while an infection in the lower back typically affects only the legs and the area around the tailbone. In the early stages of Pott’s Disease, imaging techniques such as CT scans, MRIs, or plain radiographs are ordered.
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [1] [2] First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid.
In the human skeleton, a tubercle or tuberosity is a protrusion that serves as an attachment for skeletal muscles. The muscles attach by tendons, where the enthesis is the connective tissue between the tendon and bone. [4] For example, the tibial tuberosity creates an attachment point for the ligamentum patellae, or patellar ligament.
Mycobacterium tuberculosis is the most common cause of both pulmonary tuberculosis and tuberculous lymphadenitis. [1] [6] Historically, transmission of Mycobacterium bovis from dairy consumption was another frequent cause of tuberculous lymphadenitis, but incidence has drastically decreased in developed countries since the advent of pasteurization and other efforts to prevent bovine ...
This area is known as a “Ghon focus”. TB also gets to nearby hilar lymph nodes, either carried over by immune cells through the lymph or by direct extension of the Ghon focus infection and causes caseation there as well, and together, this caseating tissue and associated lymph node make up the characteristic “Ghon complex”.