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Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease involving the gradual deterioration and death of specific volumes of the brain. [ 1 ] [ 2 ] The condition leads to symptoms including loss of balance , slowing of movement , difficulty moving the eyes , and cognitive impairment . [ 1 ]
Parkinson-plus syndromes are usually more rapidly progressive and less likely to respond to antiparkinsonian medication than PD. [10] [11] However, the additional features of the diseases may respond to medications not used in PD. [citation needed] Current therapy for Parkinson-plus syndromes is centered around a multidisciplinary treatment of ...
Progressive supranuclear palsy (PSP) without CBD is estimated to be ten times more common. CBD represents roughly 4–6% of patients with Parkinsonism. Average age at disease onset is about 64, with the youngest confirmed onset being at age 43. There may be a slight female predominance. [16]
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Near-normal life expectancy: Frequency: 8.5 million (2019) [4] Named after: ... and the tauopathies progressive supranuclear palsy and corticobasal degeneration. ...
Corticobasal syndrome and degeneration, and progressive supranuclear palsy, are usually distinguished from DLB by history and examination. ... Life expectancy is ...
Corticobasal syndrome (CBS) is a rare, progressive atypical Parkinsonism syndrome and is a tauopathy related to frontotemporal dementia. [1] [2] CBS is typically caused by the deposit of tau proteins forming in different areas of the brain. [1] [3]