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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Opioids are a class of compounds that elicit analgesic (pain killing) effects in humans and animals by binding to the μ-opioid receptor within the central nervous system. The following table lists opioid and non-opioid analgesic drugs and their relative potencies .

  3. Pain ladder - Wikipedia

    en.wikipedia.org/wiki/Pain_ladder

    The WHO guidelines recommend prompt oral administration of drugs ("by the mouth") when pain occurs, starting, if the patient is not in severe pain, with non-opioid drugs such as paracetamol (acetaminophen) or aspirin, [1] with or without "adjuvants" such as non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors.

  4. List of Schedule II controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_II...

    This is the list of Schedule II controlled substances in the United States as defined ... Drug 9050 opiate Codeine [2 ... (non-dosage forms) [10] 9743 opiate Carfentanil

  5. Vertex non-opioid painkiller meets main goal in late ... - AOL

    www.aol.com/news/vertex-non-opioid-pain-drug...

    (Reuters) -Vertex Pharmaceuticals' experimental drug reduced acute, post-surgical pain without the risk of addiction, a major milestone in the company's decades-long efforts to bring a non-opioid ...

  6. Suzetrigine - Wikipedia

    en.wikipedia.org/wiki/Suzetrigine

    Suzetrigine (developmental code name VX-548) is a non-opioid, small-molecule analgesic that works as a selective inhibitor of Na v 1.8-dependent pain-signaling pathways in the peripheral nervous system. [1] [2] It is being developed by Vertex Pharmaceuticals and has completed two phase III clinical trials. [1] [3]

  7. A New Pain Medication Could Reinforce the Disastrous ... - AOL

    www.aol.com/news/pain-medication-could-reinforce...

    Vertex Pharmaceuticals is trumpeting the results of clinical trials indicating that VX-548, its new, non-opioid analgesic, is effective at relieving post-surgical pain. While there is nothing ...

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