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Chromium toxicity refers to any poisonous toxic effect in an organism or cell that results from exposure to specific forms of chromium—especially hexavalent chromium. [1] Hexavalent chromium and its compounds are toxic when inhaled or ingested. Trivalent chromium is a trace mineral that is essential to human nutrition.
Chromium supplementation in general is subject to a certain amount of controversy as it is by no means clear that chromium is an essential element in human biology. [25] Nevertheless, chromium is an ingredient in total parenteral nutrition, along with other trace minerals. [26] It is also in nutritional products for preterm infants. [27]
Although the safety of daily chromium doses of up to 1,000 μg has been shown, there are some reports of serious adverse effects by using chromium picolinate, including kidney failure from a six-week course of 600 μg per day and liver disease after using 1,200 to 2,400 μg per day over four to five months. [2]
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A renal diet is a diet aimed at keeping levels of fluids, electrolytes, and minerals balanced in the body in individuals with chronic kidney disease or who are on dialysis. Dietary changes may include the restriction of fluid intake, protein , and electrolytes including sodium , phosphorus , and potassium . [ 1 ]
An important function of the kidneys is the removal of a wide variety of potentially toxic metabolites and metabolic wastes from the body. Elimination of unwanted substances via the urine depends ...
In its trivalent form, chromium is relatively harmless and abundant. But heat that is more than 390 degrees Fahrenheit can catalyze chemical reactions that transform it into its more dangerous ...
While chromium metal and Cr(III) ions are considered non-toxic, chromate and its derivatives, often called "hexavalent chromium", is toxic and carcinogenic. According to the European Chemicals Agency (ECHA), chromium trioxide that is used in industrial electroplating processes is a "substance of very high concern" (SVHC).