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Shop safe cat flea treatments and medicines approved by vets, including topical gels, collars, and oral tablets from Revolution, Advantage, Frontline, and more.
Flea medicines need to be used with care because many of them also affect mammals. Pyrethrin based flea treatments meant for dogs can be hazardous to cats. Flea and tick ointment is also hazardous to humans. If the product comes into contact with human skin, it is recommended to wash thoroughly with soap and water.
The US Food and Drug Administration (FDA) approved it for flea treatment in dogs in May 2014, [17] and approved the combination fluralaner/moxidectin (Bravecto Plus) as a topical treatment for cats in November 2019.
Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels.
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Poisoning in cats can result in seizures, fever, ataxia and even death. Poisoning can occur if pyrethroid containing flea treatment products, which are intended for dogs, are used on cats. The livers of cats detoxify pyrethroids via glucuronidation more poorly than dogs, which is the cause of this difference. [15]
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