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  2. DNA damage-inducible transcript 3 - Wikipedia

    en.wikipedia.org/wiki/DNA_damage-inducible...

    A summary of CHOP upstream and downstream pathways. The PERK-ATF4-CHOP pathway can induce apoptosis by binding to the death receptors and upregulating the expression of death receptor 4 (DR4) and DR5. CHOP also interacts with the phosphorylated transcription factor JUN to form a complex that binds to the promoter region of DR4 in lung cancer ...

  3. Trigeminovascular system - Wikipedia

    en.wikipedia.org/wiki/Trigeminovascular_system

    Hence, the TVS has provided a template for migraine pathophysiology and target for drug discovery. The history of some discoveries re the TV System are summarised in Ashina, et al. [13] The Brain Prize for 2021 was awarded to 4 investigators studying the trigeminovascular system and its implications for migraine pathophysiology and treatments.

  4. ICHD classification and diagnosis of migraine - Wikipedia

    en.wikipedia.org/wiki/ICHD_classification_and...

    Most children with abdominal migraines will develop migraine headache in adult life; the two propensities might co-exist during the child's adolescence. Treating an abdominal migraine can often be difficult; [10] medications used to treat other forms of migraines are usually employed. [11] These include Elavil, [12] Wellbutrin SR, [13] and ...

  5. UVA pain research suggests new ways to manage migraine ... - AOL

    www.aol.com/uva-pain-research-suggests-ways...

    By targeting progesterone receptors, researchers and clinicians can potentially modulate these pathways to mitigate migraine and other chronic pain conditions. “However, further research is ...

  6. Migraine Disability Assessment Test - Wikipedia

    en.wikipedia.org/wiki/Migraine_Disability...

    The Migraine Disability Assessment Test (MIDAS) is a test used by doctors to determine how severely migraines affect a patient's life. Patients are asked questions about the frequency and duration of their headaches, as well as how often these headaches limited their ability to participate in activities at work, at school, or at home.

  7. Yes, It's Possible To Have Migraines Without Experiencing A ...

    www.aol.com/lifestyle/yes-possible-migraines...

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  8. CHOP (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/CHOP_(chemotherapy)

    CHOP is the acronym for a chemotherapy regimen used in the treatment of non-Hodgkin lymphoma. CHOP consists of: CHOP consists of: C yclophosphamide , an alkylating agent which damages DNA by binding to it and causing the formation of cross-links

  9. This Christmas, ask for genetic testing. It could save your life.

    www.aol.com/christmas-ask-genetic-testing-could...

    Rose Brystowski, 68, had a choice to make. Others might have found it difficult. She found it easy. Brystowski, of Oak Park, Michigan, wasn't about to let her genetics forfeit her future. Doctors ...