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GLP-1 medications can help reduce hunger and promote weight loss. ... Even if you’re already taking metformin as part of your PCOS management, you may benefit from additional medications.
While it was once “just” a medication for people with type 2 diabetes, metformin is now thought of as a “wonder drug with multiple potentials,” says David Cutler, M.D., a family medicine ...
In PCOS, in addition to improved glucose markers, metformin can help to restore regular menstrual cycles, help with fertility, as well as improve acne, Dr. Wheeler notes.
It therefore concluded that the benefit of metformin in the improvement of reproductive outcomes in women with PCOS is limited. [17] The ESHRE/ASRM-sponsored Consensus workshop does not recommend metformin for ovulation stimulation. [18] Subsequent randomized studies have confirmed the lack of evidence for adding metformin to clomiphene. [19]
Polycystic ovary syndrome (PCOS) affects an estimated one in 10 women. Researchers recently found that weight loss interventions may help those with PCOS reduce weight and improve blood sugar ...
Insulin resistance in women with PCOS is typically treated with insulin-sensitizer drugs such as metformin. Metformin can help to decrease weight and androgen levels. [72] When combined with lifestyle modifications (changes in diet and exercise), it has been linked with lower body mass index and a reduction in menstrual problems. [72]
A 2017 review found that people with diabetes who were taking metformin had lower all-cause mortality. [233] They also had reduced cancer and cardiovascular disease compared with those on other therapies. [233] In people without diabetes, metformin does not appear to reduce the risk of cancer and cardiovascular disease. [239]
Kumar says that people with PCOS may be good candidates for semaglutide medications if they are overweight or obese, are not actively trying to become pregnant and have tried metformin and ...