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Metformin is available to treat type 2 diabetes as-is, and is also used with other drugs in some medications to treat diabetes, according to the U.S. National Library of Medicine. Why it's being ...
Doctors often prescribe another diabetes drug, metformin, to help with PCOS-related insulin resistance, though the drug works in a different way than GLP-1 agonists.
GLP-1 medications can help reduce hunger and promote weight loss. ... Even if you’re already taking metformin as part of your PCOS management, you may benefit from additional medications.
Insulin resistance in women with PCOS is typically treated with insulin-sensitizer drugs such as metformin. Metformin can help to decrease weight and androgen levels. [72] When combined with lifestyle modifications (changes in diet and exercise), it has been linked with lower body mass index and a reduction in menstrual problems. [72]
In PCOS, in addition to improved glucose markers, metformin can help to restore regular menstrual cycles, help with fertility, as well as improve acne, Dr. Wheeler notes.
A 2017 review found that people with diabetes who were taking metformin had lower all-cause mortality. [233] They also had reduced cancer and cardiovascular disease compared with those on other therapies. [233] In people without diabetes, metformin does not appear to reduce the risk of cancer and cardiovascular disease. [239]
It therefore concluded that the benefit of metformin in the improvement of reproductive outcomes in women with PCOS is limited. [17] The ESHRE/ASRM-sponsored Consensus workshop does not recommend metformin for ovulation stimulation. [18] Subsequent randomized studies have confirmed the lack of evidence for adding metformin to clomiphene. [19]
Polycystic ovary syndrome (PCOS) affects an estimated one in 10 women. Researchers recently found that weight loss interventions may help those with PCOS reduce weight and improve blood sugar ...