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Lemierre's syndrome is primarily treated with antibiotics given intravenously. Fusobacterium necrophorum is generally highly susceptible to beta-lactam antibiotics , metronidazole , clindamycin and third generation cephalosporins while the other fusobacteria have varying degrees of resistance to beta-lactams and clindamycin. [ 14 ]
Fusobacterium necrophorum is a species of bacteria responsible for Lemierre's syndrome. It has also been known to cause sinusitis , mastoiditis , and odontogenic infections . [ 2 ]
Strains of Fusobacterium can cause several human diseases and infections, including periodontal diseases, Lemierre's syndrome, [8] oral, head, and neck infections, as well as colorectal cancer and topical skin ulcers. [9] It has been tied [clarification needed] to HIV infection and suboptimal immune recovery. [10]
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Treatment of the acute disease is by debridement and antibiotics, usually metronidazole. Poor oral hygiene and other predisposing factors may need to be corrected to prevent recurrence. Necrotizing gingivitis is also known as trench mouth, as it was observed to occur in the mouths of front line soldiers during World War I.
F. necroporum may occasionally cause septicaemia with metastatic abscesses (Lemierre's syndrome). ... which is used to insert intravenous drugs, may become infected ...
Leiner's disease; Lelis syndrome; Lemierre's syndrome; Lennox–Gastaut syndrome; Lenz microphthalmia syndrome; Lenz–Majewski syndrome; Leriche's syndrome; Leschke syndrome; Lesch–Nyhan syndrome; Lethal congenital contracture syndrome; Lethal white syndrome; Leukotriene receptor antagonist-associated Churg–Strauss syndrome; Levator ani ...
The term Bacterium necrophorum as used by Dack might be a synonym for Fusobacterium necrophorum, which can cause Lemierre's syndrome. [12] [13] Dack, G. M.; Dragstedt, Lester R. (1938). "Effect of introducing oxygen into the isolated colon of a patient with chronic ulcerative colitis". American Journal of Digestive Diseases. 5 (2): 84– 86.