Search results
Results From The WOW.Com Content Network
Abnormal dreams; Aggression; Anaphylactic shock; Angioedema (indicative of a hypersensitivity reaction); Arthralgia; Ataxia; Blood glucose disturbances; Bronchospasm (indicative of a hypersensitivity reaction)
Bupropion prescribed for smoking cessation results in a 25% increase in the risk of psychiatric side effects, in particular, anxiety (about 40% increase) and insomnia (about 80% increase). The evidence is insufficient to determine whether bupropion is associated with suicides or suicidal behavior.
Sustained-release versions of bupropion (Wellbutrin SR, for example) can contain 100 mg, 150 mg or 200 mg. Extended-release tablets of bupropion contain either 150 mg or 300 mg.
Bupropion, on the other hand, is one of the few antidepressants that don’t cause these common side effects, and some research shows it can have the opposite effect — increasing your libido.
For example, a study published in the Journal of Clinical Medicine in 2016 found that bupropion users lost an average of 7.1 pounds over the course of two years when compared to depressed people ...
Dextromethorphan/bupropion has less activity as an NMDA receptor antagonist than dextromethorphan alone. [11] This is because bupropion is a potent CYP2D6 inhibitor and prevents the bioactivation of dextromethorphan into dextrorphan, a much more potent NMDA receptor antagonist and weaker serotonin reuptake inhibitor than dextromethorphan itself ...
The FDA added a black box warning — the most prominent drug safety warning — to bupropion packaging alerting healthcare providers and patients about potentially dangerous side effects.
Another important interaction of certain SSRIs involves paroxetine, a potent inhibitor of CYP2D6, and tamoxifen, an agent used commonly in the treatment and prevention of breast cancer. Tamoxifen is a prodrug that is metabolised by the hepatic cytochrome P450 enzyme system, especially CYP2D6, to its active metabolites.