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  2. Dofetilide - Wikipedia

    en.wikipedia.org/wiki/Dofetilide

    If the QTc is greater than 440 msec (or 500 msec in patients with ventricular conduction abnormalities), dofetilide is contraindicated. If heart rate is less than 60 bpm, the uncorrected QT interval should be used. After each subsequent dose of dofetilide, QTc should be determined and dosing should be adjusted.

  3. Drug-induced QT prolongation - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_QT_prolongation

    QT prolongation is a measure of delayed ventricular repolarisation, which means the heart muscle takes longer than normal to recharge between beats. It is an electrical disturbance which can be seen on an electrocardiogram (ECG). Excessive QT prolongation can trigger tachycardias such as torsades de pointes (TdP).

  4. Antiarrhythmic agent - Wikipedia

    en.wikipedia.org/wiki/Antiarrhythmic_agent

    The initial classification system had 4 classes, although their definitions different from the modern classification. Those proposed in 1970 were: [2] Drugs with a direct membrane action: the prototype was quinidine, and lignocaine was a key example. Differing from other authors, Vaughan-Williams describe the main action as a slowing of the ...

  5. Dronedarone - Wikipedia

    en.wikipedia.org/wiki/Dronedarone

    Dronedarone has been termed a "multichannel blocker". [citation needed] However, it is unclear which channel(s) play a pivotal role in its success. [9]Thus, dronedarone's actions at the cellular level are controversial, with most studies suggesting an inhibition in multiple outward potassium currents including rapid delayed rectifier, slow delayed rectifier and ACh-activated inward rectifier. [10]

  6. What is 'Ozempic face'? How we refer to weight-loss side ...

    www.aol.com/ozempic-face-refer-weight-loss...

    Ozempic has taken the world by storm – largely due to the medication's weight loss effect and rumored use by celebrities and the wealthy.. But some physicians want to shift this narrative ...

  7. Torsades de pointes - Wikipedia

    en.wikipedia.org/wiki/Torsades_de_pointes

    Torsades de pointes, torsade de pointes or torsades des pointes (TdP; also called torsades) (/ t ɔːr ˌ s ɑː d d ə ˈ p w æ̃ t /, [2] French: [tɔʁsad də pwɛ̃t̪], translated as "twisting of peaks") is a specific type of abnormal heart rhythm that can lead to sudden cardiac death.

  8. Man allegedly called 911 a total of 17 times and demanded a ...

    www.aol.com/news/man-allegedly-called-911-total...

    Police in East Windsor, N.J., arrested a 24-year-old man on Dec. 23, and charged him with misusing the town’s 911 system for allegedly calling emergency dispatchers a total of 17 times.

  9. Drinking Coffee Every Day Could Add Up to 2 Years to Your Life

    www.aol.com/lifestyle/drinking-coffee-every-day...

    Drinking coffee could extend your life up to two years, new research finds. Regular coffee consumption was found to be associated with increased health span (time spent living free from serious ...