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Use of barrier membranes to direct bone regeneration was first described in the context of orthopaedic research 1959. [2] The theoretical principles basic to guided tissue regeneration were developed by Melcher in 1976, who outlined the necessity of excluding unwanted cell lines from healing sites to allow growth of desired tissues. [3]
Barrier membranes have been derived from a variety of sources, both natural and synthetic, and are marketed under various trade names. Membranes used in guided bone regeneration (GBR) and grafting may be of two principal varieties: non-resorbable; resorbable.
The performance of these membranes is comparable with commercial collagen and e-PTFE membranes, showing well suitability for use in guided bone regeneration. [ 4 ] [ 6 ] Due to rubbery and hydrophobic nature, PTMC-based copolymers produced from ROP of TMC with lactone -based comonomers have been synthesized to modify these characteristics ...
Socket preservation or alveolar ridge preservation is a procedure to reduce bone loss after tooth extraction. [1] [2] After tooth extraction, the jaw bone has a natural tendency to become narrow, and lose its original shape because the bone quickly resorbs, resulting in 30–60% loss in bone volume in the first six months. [3]
It is still unclear exactly how EMD participates in the regeneration process. [5] But it has been demonstrated that EMD serves to promote periodontal ligament fibroblast proliferation and growth and inhibit epithelial cell proliferation and growth; [3] this is a key feature in EMD-promoted periodontal tissue regeneration, because the faster-growing epithelium will ordinarily compete very ...
In 1994, Nowzari challenged membrane guided tissue regeneration through a series of research publications, showing that the membrane is actually a source of infection to the grafted site. [ 7 ] Research in the field of bone grafting has been focused on autogenous sources
In dentistry, the subepithelial connective tissue graft (SECT graft, and sometimes referred to simply as a connective tissue (CT) graft) is an oral and maxillofacial surgical procedure first described by Alan Edel in 1974. [1]
Successful treatment of LPC consists of surgical removal of the lesion by conservative enucleation with guided bone regeneration technique (GBR) with xenograft and resorbable collagen membrane. This is often achieved without affecting the periodontal health of adjacent teeth.