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Diosmin is a dietary supplement used to aid treatment of hemorrhoids and venous diseases, i.e., chronic venous insufficiency including spider and varicose veins, leg swelling , stasis dermatitis and venous ulcers. [1] The mechanism of action of Diosmin and other phlebotonics is undefined, [1] and clinical evidence of benefit is limited. [1]
Flavonoids (or bioflavonoids; from the Latin word flavus, meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans.
Rutin is a citrus flavonoid glycoside found in many plants, including buckwheat, [7] the leaves and petioles of Rheum species, and asparagus. Tartary buckwheat seeds have been found to contain more rutin (about 0.8–1.7% dry weight) than common buckwheat seeds (0.01% dry weight). [7]
A vasoprotective is a medication which acts to alleviate or prevent conditions or diseases which affect the blood vessels.The term is used in the World Health Organization's Anatomical Therapeutic Chemical Classification System to encompass therapeutic agents used in the treatment of hemorrhoids or varicose veins. [1]
ATC code C05 Vasoprotectives is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Amentoflavone (bis-apigenin coupled at 8 and 3' positions); Lophirone L and lophirone M found in Lophira alata; Sulcatone A, a naturally occurring biflavonoid isolated from Ouratea sulcata.
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