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The terms flavonoid and bioflavonoid have also been more loosely used to describe non-ketone polyhydroxy polyphenol compounds, which are more specifically termed flavanoids. The three cycles or heterocycles in the flavonoid backbone are generally called ring A, B, and C. [ 2 ] Ring A usually shows a phloroglucinol substitution pattern.
Extracts of the leaves of this plant, used with and with other plant's extracts, are used in many African countries to treat some infections such as upper tract respiratory infections, dysenteria, diarrhoea and toothache. Positive antimicrobial activity has been shown in-vitro against Staphylococcus aureus and Bacillus subtilis.
Backbone of a flavonol, substituent numbers are indicated. Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name: 3-hydroxy-2-phenylchromen-4-one).
Medically, isoflavonoids and related compounds have been used in many dietary supplements but the medical and scientific community [who?] is generally skeptical of their use. Recently, some natural isoflavonoids have been identified as toxins, including biliatresone which may cause biliary atresia when infants are exposed to the plant product.
Quercetin is a flavonoid widely distributed in nature. [2] The name has been used since 1857, and is derived from quercetum (oak forest), after the oak genus Quercus. [4] [5] It is a naturally occurring polar auxin transport inhibitor.
The estimated daily intake of flavones is about 2 mg per day. [1] Following ingestion and metabolism, flavones, other polyphenols, and their metabolites are absorbed poorly in body organs and are rapidly excreted in the urine, indicating mechanisms influencing their presumed absence of metabolic roles in the body.