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  2. Management of thalassemia - Wikipedia

    en.wikipedia.org/wiki/Management_of_thalassemia

    For more severe forms, treatment may consist in blood transfusion; chelation therapy to reverse iron overload, using drugs such as deferoxamine, deferiprone, or deferasirox; medication with the antioxidant indicaxanthin to prevent the breakdown of hemoglobin; or a bone marrow transplant using material from a compatible donor, or from the ...

  3. Beta thalassemia - Wikipedia

    en.wikipedia.org/wiki/Beta_thalassemia

    Beta thalassemia minor can also present as beta thalassemia silent carriers; those who inherit a beta thalassemic mutation but have no hematologic abnormalities nor symptoms. [8] Some people with thalassemia are susceptible to health complications that involve the spleen (hypersplenism) and gallstones (due to hyperbilirubinemia from peripheral ...

  4. Thalassemia - Wikipedia

    en.wikipedia.org/wiki/Thalassemia

    Iron overload may be moderated with chelation drugs. [4] [10] If the spleen becomes overly enlarged, surgical removal may be required. [1] Beta thalassemia may be treated with hydroxyurea. [11] Thalidomide has been trialled as a treatment for beta thalassemia, but it has not been licensed in a clinical setting. [12]

  5. Luspatercept - Wikipedia

    en.wikipedia.org/wiki/Luspatercept

    Luspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [5] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [8]

  6. Betibeglogene autotemcel - Wikipedia

    en.wikipedia.org/wiki/Betibeglogene_autotemcel

    Betibeglogene autotemcel, sold under the brand name Zynteglo, is a gene therapy for the treatment for beta thalassemia. [1] [5] [2] It was developed by Bluebird Bio and was given breakthrough therapy designation by the US Food and Drug Administration in February 2015.

  7. Deferiprone - Wikipedia

    en.wikipedia.org/wiki/Deferiprone

    Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. [5] It was first approved and indicated for use in treating thalassaemia major in 1994 [6] and had been licensed for use in the European Union for many years while awaiting approval in Canada and in the United States. [5]

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