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Rigid spine syndrome, also known as congenital muscular dystrophy with rigidity of the spine (CMARS), is a rare and often debilitating neuromuscular disorder. It is characterized by progressive muscle stiffness and rigidity, particularly in the spine, which can severely limit mobility and impact quality of life. This condition is typically ...
Symptoms associated with central nervous systems disorders are classified into positive and negative categories. Positive symptoms include those that increase muscle activity through hyper-excitability of the stretch reflex (i.e., rigidity and spasticity) where negative symptoms include those of insufficient muscle activity (i.e. weakness) and reduced motor function. [5]
Progressive encephalomyelitis with rigidity and myoclonus (PERM) [4] Muscle stiffness and contraction can cause abnormal resting postures. Around 70% of those with SPS have the "classic" form of the disease. [5] People with classic SPS typically first experience intermittent tightness or aching in the muscles of the trunk. [6]
Hypokinesia is characterized by a partial or complete loss of muscle movement due to a disruption in the basal ganglia. [citation needed] Hypokinesia is a symptom of Parkinson's disease shown as muscle rigidity and an inability to produce movement. It is also associated with mental health disorders and prolonged inactivity due to illness ...
They include movement dysfunction such as dystonia (continuous spasms and muscle contractions), akathisia (may manifest as motor restlessness), [1] parkinsonism characteristic symptoms such as rigidity, bradykinesia (slowness of movement), tremor, and tardive dyskinesia (irregular, jerky movements). [2]
The signs and symptoms of Serotonin Syndrome include: Agitation or restlessness. Insomnia. Dilated pupils. Loss of muscle coordination or twitching muscles. Muscle rigidity. Tremor. Heavy sweating ...
Rigidity is characterized by an increased muscle tone (an excessive and continuous contraction of the muscles) which produces stiffness and resistance to movement in joints. [1] Rigidity may be associated with joint pain, with such pain being a frequent initial manifestation of the disease. [1]
The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1] Symptoms include delayed relaxation of the muscles after voluntary contraction (myotonia), and may also include stiffness, hypertrophy (enlargement), transient weakness in some forms of the ...