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The "a calorie is a calorie" model of obesity posits a combination of excessive food energy intake and a lack of physical activity as the cause of most cases of obesity. [96] A limited number of cases are due primarily to genetics, medical reasons, or psychiatric illness. [ 15 ]
Pathophysiology of obesity is the study of disordered physiological processes that cause, result from, or are otherwise associated with obesity. A number of possible pathophysiological mechanisms have been identified which may contribute in the development and maintenance of obesity.
Obesity is a chronic health problem. It is one of the biggest factors for type II diabetes and cardiovascular disease.It is also associated with cancer (e.g. colorectal cancer), osteoarthritis, liver disease, sleep apnea, depression, and other medical conditions that affect mortality and morbidity.
Certain genetic conditions can also cause obesity. For example, Prader-Willi syndrome is an inherited disorder that leads to, among other complications, intellectual disability, a short stature ...
Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity.
Obesity has been observed throughout human history. Many early depictions of the human form in art and sculpture appear obese. [2] However, it was not until the 20th century that obesity became common — so much so that, in 1997, the World Health Organization (WHO) formally recognized obesity as a global epidemic [3] and estimated that the worldwide prevalence of obesity has nearly tripled ...
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