Search results
Results From The WOW.Com Content Network
The hypothalamic-pituitary-thyroid axis. TRH can be seen in green. TRH is synthesized within parvocellular neurons of the paraventricular nucleus of the hypothalamus. [2] It is translated as a 242-amino acid precursor polypeptide that contains 6 copies of the sequence -Gln-His-Pro-Gly-, with both ends of the sequence flanked by Lys-Arg or Arg-Arg sequences.
The abbreviation TRH can refer to Thyrotropin-releasing hormone; Their Royal Highnesses, style when referring to several royals; The Right Honourable, honorific style applied to certain persons in the Commonwealth of Nations
The TRH stimulates the anterior pituitary to produce thyroid-stimulating hormone (TSH). The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts negative feedback control over the hypothalamus as well as anterior pituitary, thus controlling the release of both TRH ...
TRH-stimulation testing however continues to be useful for the differential diagnosis of secondary (pituitary disorder) and tertiary (hypothalamic disorder) hypothyroidism. Patients with these conditions appear to have physiologically inactive TSH in their circulation that is recognized by TSH assays to a degree such that they may yield ...
IRC—Internet Relay Chat; IrDA—Infrared Data Association; IRI—Internationalized Resource Identifier; IRP—I/O Request Packet; IRQ—Interrupt Request; IS—Information Systems; IS-IS—Intermediate System to Intermediate System; ISA—Industry Standard Architecture; ISA—Instruction Set Architecture; ISAM—Indexed Sequential Access Method
For premium support please call: 800-290-4726 more ways to reach us
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
TRH stimulates the thyrotropic cells through the use of a phospholipase C second messenger system. [1] TRH binds to a class A G protein-coupled receptor on the surface of a thyrotropic cell, which is known as the thyrotropin-releasing hormone receptor (TRHR). Strong hydrogen bonding interactions stabilize the binding of TRH to TRHR.