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Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol. It can lead to cardiac failure , rhabdomyolysis , metabolic acidosis , and kidney failure , and is often fatal.
APACHE II ("Acute Physiology and Chronic Health Evaluation II") is a severity-of-disease classification system, [1] one of several ICU scoring systems.It is applied within 24 hours of admission of a patient to an intensive care unit (ICU): an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death.
The first PICU in the United States is a topic often debated. Currently, Fuhrman’s Textbook in Pediatric Critical Care lists Pediatric Critical Care Unit at the Children’s Hospital of District of Columbia in Washington, DC, dating back to 1965, as the first pediatric critical care unit in the U.S.A. Medical Director was Dr. Berlin. [6]
Intensive care medicine, usually called critical care medicine, is a medical specialty that deals with seriously or critically ill patients who have, are at risk of, or are recovering from conditions that may be life-threatening. [1]
Lankenau Medical Center, part of Main Line Health, is a 370-bed acute care, teaching hospital in Wynnewood, Pennsylvania.. Lankenau Medical Center's clinical areas include the Lankenau Heart Institute, the gastrointestinal and GI endoscopy program, cancer care services, pulmonology, orthopaedics, obstetrics and maternity, including and a level III neonatal intensive care unit, as well as ...
To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. [13]It is often administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI).
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Several studies in the 1980s seemed to show a benefit of the increase in physiological information. Many reports showing benefit of the PA catheter are from anaesthetic, and Intensive Care Unit (ICU) settings. In these settings cardiovascular performance was optimized thinking patients would have supra-normal metabolic requirements.