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Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. [1] It is also used to prevent malaria.
A new proven protocol in which doxycycline is used to prevent sexually transmitted infections — called doxyPEP — has been an apparent sleeper hit among gay and bisexual men.
Health care providers should consider prescribing a commonly used antibiotic to certain people as a way to prevent chlamydia, gonorrhea and syphilis infections, according to a draft recommendation ...
The symptoms of syphilis have become less severe over the 19th and 20th centuries, in part due to widespread availability of effective treatment, and partly due to virulence of the bacteria. [23] With early treatment, few complications result. [22]
Doxycycline is also used as a prophylactic treatment for infection by Bacillus anthracis and is effective against Yersinia pestis, the infectious agent of bubonic plague. It is also used for malaria treatment and prophylaxis, as well as treating elephantitis filariasis . [ 10 ]
Overall, prevention of congenital syphilis with prenatal screening for maternal syphilis is the best treatment. Effective prevention requires routine prenatal screening, rapid treatment of all infected mothers, and partner tracing/treatment. Additionally, improved health education on STIs and safe sexual practices is essential.
Of the 660,000 congenital syphilis cases reported in 2016, 143,000 resulted in deaths of unborn babies, 61,000 deaths of newborn babies, 41,000 low birth weights or preterm births, and 109,000 young children diagnosed with congenital syphilis. [15] Around 75% were from the WHO's African and Eastern Mediterranean regions. [2]
Michigan saw a 200% increase in the rate of congenital syphilis from 2017-2021, as a rising number of babies in the U.S. are born with the infection.