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The Sign of Hertoghe or Queen Anne's sign is a thinning or loss of the outer third of the eyebrows, and is a classical sign of hypothyroidism or atopic dermatitis, [1] [2] [3] but it can also be detected in lepromatous leprosy. [4]
In medical literature, Anglo-Irish surgeon Robert James Graves, in 1835, was the first to describe the association of a thyroid goitre with exophthalmos (proptosis) of the eye. [29] Graves' ophthalmopathy may occur before, with, or after the onset of overt thyroid disease and usually has a slow onset over many months. [citation needed]
Graves' disease data has shown that the lifetime risk for women is around 3% and 0.5% for men. [39] It occurs about 7.5 times more often in women than in men [1] and often starts between the ages of 40 and 60. [6] It is the most common cause of hyperthyroidism in the United States (about 50 to 80% of cases). [1] [4]
Thinning eyebrows. Another classic sign of hypothyroidism is losing the outer third of your eyebrows, which is sometimes called “Queen Anne’s sign” in reference to an ancient portrait. “I ...
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Anxiety syndromes related to hyperthyroidism are typically complicated by major depression and cognitive decline, such as in memory and attention. [30] Some studies contradict the psychological findings. For example, a large 2002 study found "no statistical association between thyroid dysfunction, and the presence of depression or anxiety ...
Musician, model and eyebrow inspiration of the moment Gabriette Bechtel at her birthday party in Los Angeles in July 2024. - Rachpoot/Bauer-Griffin/GC Images/Getty Images
Madarosis is not a critical or severe condition. The main symptom and sign of madarosis is the loss of hair from the eyelids, eyebrows, or eyelashes. Many symptoms are from other diseases involved. Swollen, itchy, red, burning eyelids; Loss of hair from other parts of the body, mainly the scalp; Weight gain or palpitation if there is a thyroid ...