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  2. Essential thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Essential_thrombocythemia

    In hematology, essential thrombocythemia (ET) is a rare chronic blood cancer (myeloproliferative neoplasm) characterised by the overproduction of platelets (thrombocytes) by megakaryocytes in the bone marrow. [3] It may, albeit rarely, develop into acute myeloid leukemia or myelofibrosis. [3]

  3. Thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Thrombocythemia

    The condition arises from a fault in the bone marrow cells leading to over-production of platelets but the cause of the fault is unknown, and this type is not common. [2] When the cause is known such as another disorder or disease, the term thrombocytosis is preferred, as either secondary or reactive thrombocytosis. Reactive thrombocytosis is ...

  4. Trousseau sign of malignancy - Wikipedia

    en.wikipedia.org/wiki/Trousseau_sign_of_malignancy

    Some adenocarcinomas secrete mucin that can interact with selectin found on platelets, thereby causing small clots to form. [8] [9] Moreover, most malignant tumors overexpress and secrete heparanase, [10] an enzyme that degrade heparan sulfate [11] and endogenous heparin, [12] and thus contribute to the hypercoagulable state in cancer patients ...

  5. Myeloproliferative neoplasm - Wikipedia

    en.wikipedia.org/wiki/Myeloproliferative_neoplasm

    Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.

  6. Megakaryocyte - Wikipedia

    en.wikipedia.org/wiki/Megakaryocyte

    Essential thrombocythemia (ET) is a disorder characterized by elevated numbers of circulating platelets. The disease occurs in 1–2 per 100,000 people. The disease occurs in 1–2 per 100,000 people.

  7. Platelet - Wikipedia

    en.wikipedia.org/wiki/Platelet

    Platelets or thrombocytes ... Elevated platelet concentration is called thrombocytosis, ... Cancer [64] Malaria [65]

  8. Giant platelet disorder - Wikipedia

    en.wikipedia.org/wiki/Giant_platelet_disorder

    Giant platelet disorder; Two giant platelets (stained purple) are visible in this image from a light microscope (40×) from a peripheral blood smear surrounded by red blood cells. One normal platelet can be seen in the upper left side of the image (purple) and is significantly smaller in size than the red blood cells (stained pink). Specialty ...

  9. Plateletpheresis - Wikipedia

    en.wikipedia.org/wiki/Plateletpheresis

    Platelet donation therapy is frequently needed by cancer patients, because chemotherapy for such patients can render them unable to generate platelets of their own. The basic principles of automatic platelet apheresis are the same as in the manual procedure, but the whole procedure is performed by a computer-controlled machine. Since the donor ...

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