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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. [13]It is often administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI).
Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol. It can lead to cardiac failure , rhabdomyolysis , metabolic acidosis , and kidney failure , and is often fatal.
Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
Its units are in parts per million (ppm) for gases and in milligrams per cubic meter (mg/m 3) for particulates such as dust, smoke and mist. The basic formula for converting between ppm and mg/m 3 for gases is ppm = (mg/m^3) * 24.45 / molecular weight. This formula is not applicable to airborne particles.
kilogram per cubic metre (SI unit) kg/m 3: ≡ kg/m 3 = 1 kg/m 3: kilogram per litre kg/L ≡ kg/L = 1000 kg/m 3: ounce (avoirdupois) per cubic foot oz/ft 3: ≡ oz/ft 3: ≈ 1.001 153 961 kg/m 3: ounce (avoirdupois) per cubic inch oz/in 3: ≡ oz/in 3: ≈ 1.729 994 044 × 10 3 kg/m 3: ounce (avoirdupois) per gallon (imperial) oz/gal ≡ oz ...
Multivitamins nutrition facts label showing that the international unit of, for example, vitamins D and E correspond to different gram values. In pharmacology, the international unit (IU) is a unit of measurement for the effect or biological activity of a substance, for the purpose of easier comparison across similar forms of substances.
Fospropofol is metabolized in the liver by alkaline phosphatases to propofol, formaldehyde, and phosphate.The hepatic metabolism of this prodrug to an active metabolite means that peak plasma levels of propofol after the administration of a bolus of fospropofol are lower than for an equipotent dose of propofol and also that its clinical effect is more sustained.