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  2. Tricyclic antidepressant overdose - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant...

    If sodium bicarbonate therapy fails to improve cardiac symptoms, conventional antidysrhythmic drugs or magnesium can be used to reverse any cardiac abnormalities. However, no benefit has been shown from Class 1 antiarrhythmic drugs ; it appears they worsen the sodium channel blockade, slow conduction velocity, and depress contractility and ...

  3. Hyperkalemia - Wikipedia

    en.wikipedia.org/wiki/Hyperkalemia

    Hyperkalemia is an elevated level of potassium (K +) in the blood. [1] Normal potassium levels are between 3.5 and 5.0 mmol/L (3.5 and 5.0 mEq/L) with levels above 5.5 mmol/L defined as hyperkalemia.

  4. QRS complex - Wikipedia

    en.wikipedia.org/wiki/QRS_complex

    QRS duration: 75 to 105 ms [3] Shorter in children [4] Prolonged duration could indicate hyperkalemia [5] or intraventricular conduction delay such as bundle branch block. QRS amplitude: S amplitude in V1 + R amplitude in V5 < 3.5 millivolt (mV) [4] R+S in a precordial lead < 4.5 mV [4] R in V5 or V6 < 2.6 mV; Increased amplitude indicates ...

  5. Flecainide - Wikipedia

    en.wikipedia.org/wiki/Flecainide

    Flecainide is a medication used to prevent and treat abnormally fast heart rates. [1] This includes ventricular and supraventricular tachycardias. [1] Its use is only recommended in those with dangerous arrhythmias or when significant symptoms cannot be managed with other treatments. [1]

  6. Drug-induced QT prolongation - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_QT_prolongation

    Class III antiarrhythmic drugs are potassium channel blockers that cause QT prolongation and are associated with TdP. Amiodarone. Amiodarone works in many ways. It blocks sodium, potassium, and calcium channels, as well as alpha and beta adrenergic receptors. Because of its multiple actions, amiodarone causes QT prolongation but TdP is rarely ...

  7. Intravenous sodium bicarbonate - Wikipedia

    en.wikipedia.org/wiki/Intravenous_sodium_bicarbonate

    Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. [2] For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea , vomiting , or the kidneys . [ 3 ]

  8. Sodium lactate - Wikipedia

    en.wikipedia.org/wiki/Sodium_lactate

    Sodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimetics which can cause hypertension. [10]It can be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake (for sodium bicarbonate) whose oxidative processes are not seriously ...

  9. Hypernatremia - Wikipedia

    en.wikipedia.org/wiki/Hypernatremia

    Normal volume hypernatremia can be due to fever, extreme thirst, prolonged increased breath rate, diabetes insipidus, and from lithium among other causes. [1] High volume hypernatremia can be due to hyperaldosteronism, excessive administration of intravenous normal saline or sodium bicarbonate, or rarely from eating too much salt.