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  2. Certolizumab pegol - Wikipedia

    en.wikipedia.org/wiki/Certolizumab_pegol

    Certolizumab pegol, sold under the brand name Cimzia, is a biopharmaceutical medication for the treatment of Crohn's disease, [4] [5] rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. It is a fragment of a monoclonal antibody specific to tumor necrosis factor alpha (TNF-α) and is manufactured by UCB. [6] [7] [2]

  3. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    The top 5 best selling pharmaceuticals 2015–2019. Sales in billion USD. ... Brand Name(s) Generic Name Sales Q1 2014 Sales ... Crohn's disease; Rheumatoid arthritis ...

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    inflammatory bowel disease, ulcerative colitis, Crohn's disease: Actoxumab [6] mab: human: Clostridioides difficile: Clostridioides difficile colitis: Adalimumab [7] Humira: mab: human: TNF-α: Y [8] rheumatoid arthritis, Crohn's disease, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, hemolytic ...

  5. Vedolizumab - Wikipedia

    en.wikipedia.org/wiki/Vedolizumab

    Vedolizumab, sold under the brand name Entyvio, is a monoclonal antibody medication developed by Takeda Oncology for the treatment of ulcerative colitis and Crohn's disease. [5] It binds to integrin α 4 β 7 ( LPAM-1 , lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7 ), [ 5 ] [ 6 ] blocking the α 4 ...

  6. Management of Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Crohn's_disease

    Maintenance of remission after surgery for Crohn's disease [12] A combination of azathioprine and infliximab treatment may be more effective than a single dose of infliximab to induce steroid-free remission for people with active Crohn's disease. [9] Azathioprine treatment may lead to rare but life-threatening side effects.

  7. Lilly beefs up bowel disease drug portfolio with $3.2 billion ...

    www.aol.com/news/eli-lilly-buy-bowel-disease...

    By Sriparna Roy (Reuters) -Eli Lilly agreed to buy Morphic Holding for $3.2 billion in cash, the companies said on Monday, beefing up its portfolio of inflammatory bowel disease (IBD) drugs and ...

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