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[3] [4] [5] Amphipols can be used to fold denatured membrane proteins to their native form [6] [7] and have proven particularly precious in the field of single-particle electron cryo-microscopy (cryo-EM; see e.g. [8] [9]).The properties and uses of amphipols and other non-conventional surfactants are the subject of a book by Jean-Luc Popot. [10]
A typical amphiphilic flexible surfactant can form aggregates through a self-assembly process that results of specific interactions between the molecules of the amphiphilic mesogen and those of the non-mesogenic solvent. In aqueous media, the driving force of the aggregation is the "hydrophobic effect". The aggregates formed by amphiphilic ...
In chemistry, an amphiphile (from Greek αμφις (amphis) 'both' and φιλíα 'love, friendship'), or amphipath, is a chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving, nonpolar) properties. [1] Such a compound is called amphiphilic or amphipathic.
Micelle (polymers) Organized auto-assembly formed in a liquid and composed of amphiphilic macromolecules, in general amphiphilic di- or tri-block copolymers made of solvophilic and solvophobic blocks. Note 1: An amphiphilic behavior can be observed for water and an organic solvent or between two organic solvents. Note 2
Peptide amphiphiles were developed in the 1990s. They were first described by the group of Matthew Tirrell in 1995. [5] [6] These first reported PA molecules were composed of two domains: one of lipophilic character and another of hydrophilic properties, which allowed self-assembly into sphere-like supramolecular structures as a result of the association of the lipophilic domains away from the ...
Nanoparticle monolayers can be used to create functional surfaces that have for instance anti-reflective or superhydrophobic properties. [2] [3] Monolayers are frequently encountered in biology. A micelle is a monolayer, and the phospholipid lipid bilayer structure of biological membranes is technically two monolayers. Langmuir monolayers are ...
An amphiphilic molecule is one that contains both a hydrophobic and hydrophilic domain (e.g. soaps and detergents). The LB trough allows investigators to prepare a monolayer of amphiphilic molecules on the surface of a liquid, and then compress or expand these molecules on the surface, thereby modifying the molecular density, or area per molecule.
[10] There are many properties of polymeric materials that influence their mechanical properties. As the degree of polymerization goes up, so does the polymer’s strength, as a longer chains have high Van der Waals interactions and chain entanglement. Long polymers can entangle, which leads to a subsequent increase in bulk modulus. [11]