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A negative coagulase test would instead show the presence of coagulase-negative organisms such as S. epidermidis or S. saprophyticus. However, it is now known that not all S. aureus are coagulase-positive. [2] [3] Whereas coagulase-positive staphylococci are usually pathogenic, coagulase-negative staphylococci are more often associated with ...
Some staphylococci are capable of producing free coagulase. Thus, that is used to differentiate Staphylococcus species. In this context, a distinction is made in species between coagulase-positive and coagulase-negative staphylococci. Staphylococcus capitis is a species in the genus that is positive for staph coagulase. [6]
S. epidermidis, a coagulase-negative staphylococcus species, is a commensal of the skin, but can cause severe infections in immune-suppressed patients and those with central venous catheters. S. saprophyticus , another coagulase -negative species that is part of the normal vaginal flora , is predominantly implicated in uncomplicated lower ...
Staphylococcus caprae occurs as a commensal on human skin, but has also been implicated in infections of the bloodstream, urinary tract, bones, and joints.Because S. caprae is difficult to identify definitively in the laboratory, [1] according to a study in 2014, the incidence of S. caprae in humans is under-reported.
Staphylococcus species are facultative anaerobes (capable of growth both aerobically and anaerobically). [15] All species grow in the presence of bile salts. All strains of Staphylococcus aureus were once thought to be coagulase-positive, but this has since been disproven. [16] [17] [18] Growth can also occur in a 6.5% NaCl solution. [15]
In the laboratory, it can give a positive slide-coagulase test but a negative tube-coagulase test. It is fairly easy to identify because, unlike the great majority of staphylococci, it decarboxylates ornithine and is positive for pyrrolidonyl arylamidase. [4] In the past, it was frequently misidentified as S. hominis, S. aureus, or other species.
Staphylococcus hominis is a coagulase-negative member of the bacterial genus Staphylococcus, consisting of Gram-positive, spherical cells in clusters. It occurs very commonly as a generally harmless commensal on human and animal skin and is known for producing thioalcohol compounds that contribute to body odour .
Staphylococcus cohnii is a Gram-positive, coagulase-negative member of the bacterial genus Staphylococcus consisting of clustered cocci.The species commonly lives on human skin; clinical isolates have shown high levels of antibiotic resistance. [1]