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The tunica intima (Neo-Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells (and macrophages in areas of disturbed blood flow), [1] [2] and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.
However, smooth muscle cells from the tunica media layer of the artery moved into the tunica intima, where the function of the smooth muscle cells changed from contractile function into pro-inflammatory function. This causes the fibrosis of the arterial wall, with reduction of number of smooth muscle cells, abnormal collagen synthesis ...
These cells have unique functions that include fluid filtration, such as in the glomerulus of the kidney, blood vessel tone, hemostasis, neutrophil recruitment, and hormone trafficking. Endothelium of the interior surfaces of the heart chambers is called endocardium. An impaired function can lead to serious health issues throughout the body.
Micrograph showing the internal elastic lamina (thin pink wavy line - image edge mid-left to image edge bottom-centre-left). H&E stain.. The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels.
The structure of the vasa vasorum varies with the size, function and location of the vessels. Cells need to be within a few cell-widths of a capillary to stay alive. In the largest vessels, the vasa vasorum penetrates the outer (tunica adventitia) layer and middle (tunica media) layer almost to the inner (tunica intima) layer.
Tunica mucosa is the predominant Latin rendering of "mucous membrane" in English-speaking countries, though membrana mucosa also is acceptable and in some European languages is preferred. The name may be qualified in referring to particular regions of the body, such as tunica mucosa oris for the oral mucosa, and tunica mucosa uteri for the ...
As Alzheimer’s disease is the most common form of dementia — affecting an estimated 6.7 million Americans — it’s not surprising that people who experience memory loss may suspect AD.. In ...
Arterial dissection of the carotid arteries is a condition that arises when a small tear forms in the innermost lining of the arterial wall, known as the tunica intima. This tear allows blood to enter the space between the inner and outer layers of the vessel, leading to either narrowing or complete occlusion. Notably, the stenosis in the early ...