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Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]
Fitz-Hugh–Curtis syndrome occurs almost exclusively in women, though it can be seen in males rarely. [5] It is complication of pelvic inflammatory disease (PID) caused by Chlamydia trachomatis (Chlamydia) or Neisseria gonorrhoeae (Gonorrhea) though other bacteria such as Bacteroides, Gardnerella, E. coli and Streptococcus have also been found to cause Fitz-Hugh–Curtis syndrome on occasion. [6]
HELLP syndrome patients experience general discomfort followed by severe epigastric pain or right upper abdominal quadrant pain, accompanied by nausea, vomiting, backache, anaemia, and hypertension. Some patients may also have a headache and visual issues. These symptoms may also become more severe at night.
The ligament pulls on nerve fibers and sensitive structures of the female reproductive system. Since the uterus tends to be oriented towards the right side of the body, the pain is also often felt on the right side. This leads to frequent confusion with appendicitis. [6] During pregnancy, the uterus expands to accommodate the growing fetus.
Though 40-50% of patients are asymptomatic, commonly reported symptoms include abdominal pain in the right upper quadrant, pruritus, jaundice, fatigue, and fever. [40] [41] The most common signs are hepatomegaly and splenomegaly. [40] Prolonged cholestasis in PSC may cause fat-soluble vitamin deficiency leading to osteoporosis [40]
Diagram of the regions (or quadrants) of the abdomen, to assist in locating the right upper quadrant or the epigastric region, where eclampsia-associated pain may occur. Eclampsia is a disorder of pregnancy characterized by seizures in the setting of pre-eclampsia. [17] Most women have premonitory signs/symptoms in the hours before the initial ...
Acute non-localized pain in the right upper quadrant or right lower quadrant (in concurrent fever and leukocytosis) [3] Acute pelvic pain when a non-gynecological cause is suspected [3] Suspected biliary disease such as jaundice [3] Suspected pancreatic disease [3] New‐onset severe headache [3] Newly diagnosed cancer [3]
Differentiating upper right quadrant pain In medicine , Murphy's sign (also known as Sweeney’s sign ) is a maneuver during a physical examination as part of the abdominal examination . [ 1 ] It is useful for differentiating pain in the right upper quadrant .