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Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. [2] For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea , vomiting , or the kidneys . [ 3 ]
Sodium bicarbonate (IUPAC name: sodium hydrogencarbonate [9]), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO 3. It is a salt composed of a sodium cation (Na +) and a bicarbonate anion (HCO 3 −). Sodium bicarbonate is a white solid that is crystalline but often appears as a
ATC code B05 Blood substitutes and perfusion solutions is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
In the brain, the sodium bicarbonate transporter is predominantly expressed by astrocytes. [8] They may participate in regulation of brain extracellular space pH. [9] Some mutations in the gene have been associated with familial hemiplegic migraine. [10] Other mutations disrupt kidney bicarbonate transport and cause proximal renal tubular ...
Intraosseous access has roughly the same absorption rate as IV access, and allows for fluid resuscitation. For example, sodium bicarbonate can be administered IO during a cardiac arrest when IV access is unavailable. [1] High flow rates are attainable with an IO infusion, up to 125 milliliters per minute.
Metabolic alkalosis is an acid-base disorder in which the pH of tissue is elevated beyond the normal range (7.35–7.45). This is the result of decreased hydrogen ion concentration, leading to increased bicarbonate (HCO − 3), or alternatively a direct result of increased bicarbonate concentrations.
It is measured, along with chloride, potassium, and sodium, to assess electrolyte levels in an electrolyte panel test (which has Current Procedural Terminology, CPT, code 80051). [ citation needed ] The parameter standard bicarbonate concentration (SBC e ) is the bicarbonate concentration in the blood at a P a CO 2 of 40 mmHg (5.33 kPa), full ...
Routes of administration are usually classified by application location (or exposition). The route or course the active substance takes from application location to the location where it has its target effect is usually rather a matter of pharmacokinetics (concerning the processes of uptake, distribution, and elimination of drugs).