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The drug is used to treat acute and chronic pain. It has shown effectiveness in the treatment of fibromyalgia, though it is not specifically approved for this purpose. The drug is also under investigation as an antidepressant and for the treatment of neuropathic pain. It is related in chemical structure to venlafaxine.
The Texas Medication Algorithm Project (TMAP) [1] is a decision-tree medical algorithm, the design of which was based on the expert opinions of mental health specialists.It has provided and rolled out a set of psychiatric management guidelines for doctors treating certain mental disorders within Texas' publicly funded mental health care system, along with manuals relating to each of them The ...
Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
A 2012 meta-analysis concluded that antidepressant treatment favorably affects pain, health-related quality of life, depression, and sleep in fibromyalgia syndrome. Tricyclics appear to be the most effective class, with moderate effects on pain and sleep, and small effects on fatigue and health-related quality of life.
A general anxiety disorder (GAD) algorithm was released in 2006. Periodic updates of the algorithms are released as the basis of evidence changes. In addition, the algorithms are being translated into various non-English languages (Chinese, Japanese, Spanish, and Thai) as the availability of translators permits. [citation needed]
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Mindfulness-based stress reduction is an eight-week program that helps train people to help with their stress, anxiety, depression, and pain. It was developed by Jon Kabat-Zinn in the 1970s. The program uses a combination of mindfulness meditation , body awareness, yoga , and exploration of patterns of behavior, thinking, feeling, and action.
Sequenced Treatment Alternatives to Relieve Depression (STAR*D) was a collaborative study on the treatment of depression, funded by the National Institute of Mental Health. Its main focus was on the treatment of depression in patients where the first prescribed antidepressant proved inadequate.