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The stool guaiac test involves fasting from iron supplements, red meat (the blood it contains can turn the test positive), certain vegetables (which contain a chemical with peroxidase properties that can turn the test positive), and vitamin C and citrus fruits (which can turn the test falsely negative) for a period of time before the test.
Fecal occult blood testing (FOBT), as its name implies, aims to detect subtle blood loss in the gastrointestinal tract, anywhere from the mouth to the colon.Positive tests ("positive stool") may result from either upper gastrointestinal bleeding or lower gastrointestinal bleeding and warrant further investigation for peptic ulcers or a malignancy (such as colorectal cancer or gastric cancer).
The newer and recommended tests look for globin, DNA, or other blood factors including transferrin, while conventional stool guaiac tests look for heme. Cancers, and to a lesser extent, precancerous lesions, shed abnormal cells into the stool. [4]
The stool guaiac test (or guaiac fecal occult blood test) is conducted to detect the presence of blood in stool that is not apparent to the unaided eye. The main pathogens that are commonly looked for in feces include: Bacteroides species; Salmonella and Shigella; Yersinia tends to be incubated at 30 °C (86 °F), which is cooler than usual
Melena is a form of blood in stool which refers to the dark black, tarry feces that are commonly associated with upper gastrointestinal bleeding. [1] The black color and characteristic strong odor are caused by hemoglobin in the blood being altered by digestive enzymes and intestinal bacteria.
Gum guaicum, or guaiac resin, [2] is a substance produced from the tree species Guaiacum officinale. It is registered as food additive: as a preservative under the E number E241 , and as an antioxidant under E314 .
Guaiac can refer to: Guaiacum, a genus of shrubs and trees native to the Americas; Oil of guaiac, a fragrance used in soap; Guaiacol, a natural organic compound derived from Guaiacum; Stool guaiac test, a test for the presence for occult blood
A positive aspirate is more helpful than a negative aspirate (If the aspirate is positive, an upper gastrointestinal bleed is likely; if the aspirate is negative, the source of a gastrointestinal bleed is probably, but not certainly, lower).