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  2. Adalimumab - Wikipedia

    en.wikipedia.org/wiki/Adalimumab

    The best-selling drugs list published by Genetic Engineering & Biotechnology News, shows that Humira occupied the #1 position for 2015 (US$14.012 billion) and 2016 (US$16.078 billion) [99] From 2012 until the US patent expired in 2016, Humira led the list of top-selling pharmaceutical products, and in 2016, it had US$16 billion of global sales ...

  3. TNF inhibitor - Wikipedia

    en.wikipedia.org/wiki/TNF_inhibitor

    A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...

  4. Management of Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Crohn's_disease

    It has been shown to be useful in the treatment of mild to moderate Crohn's disease, [6] and in maintaining remission. [7] It is also effective when used in combination with antibiotics to treat active Crohn's disease. [8] Budesonide is released in the ileum and right colon, and therefore has a topical effect against disease in that area. [6]

  5. Cigna to remove AbbVie's Humira from some drug ... - AOL

    www.aol.com/news/cigna-remove-abbvies-humira...

    Humira was once the world's biggest selling prescription medicine with peak sales of $21.2 billion in 2022. Express Scripts and UnitedHealth Group's Optum Rx - two of the largest PBMs - chose to ...

  6. AbbVie's tight grip on Humira market raises concerns about ...

    www.aol.com/news/abbvies-tight-grip-humira...

    AbbVie’s top-selling arthritis drug Humira has held onto more than 80% of patients after facing nine lower-priced rivals in the U.S. in the last year, raising questions about whether the market ...

  7. CVS will remove AbbVie's Humira from some drug ... - AOL

    www.aol.com/news/cvs-remove-abbvies-humira-drug...

    CVS Health said on Wednesday it will remove AbbVie’s blockbuster rheumatoid arthritis drug Humira from some of its lists of preferred drugs for reimbursement as of April 1, and will recommend ...

  8. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Humira 10.1 13.5 16.3 18.4 21.4 2 apixaban: anticoagulant: ... 4.3 6.5 Best selling pharmaceuticals of 2017/18 ... Crohn's disease; rheumatoid arthritis:

  9. UnitedHealth to remove AbbVie's Humira from some US drug ...

    www.aol.com/news/unitedhealth-remove-abbvies...

    The U.S. market share for Humira biosimilars stands at nearly 20%, compared with 2.2% in the first quarter of this year, Barclays analysts said in a note on Monday.