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Piperidine and its derivatives are ubiquitous building blocks in the synthesis of many pharmaceuticals and fine chemicals. 2-Diphenylmethylpyrrolidine , Desoxy-D2PM, 2-Benzhydrylpyrrolidine 3,4-Dichloromethylphenidate , 3,4-CTMP
The FDA said it found evidence the companies' websites offer the products, labeled for "research use only", for sale in the United States accompanied by claims such as weight loss, reducing the ...
One characteristic of a research chemical is that it is for laboratory research use only; a research chemical is not intended for human or veterinary use. This distinction is required on the labels of research chemicals and exempts them from regulation under parts 100-740 in Title 21 of the Code of Federal Regulations . [1]
α-Pyrrolidinopentiophenone (α-PVP), also known as α-pyrrolidinovalerophenone, O-2387, β-keto-prolintane, prolintanone, [2] [3] or desmethylpyrovalerone, is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug and often consumed for recreational reasons.
[5] 3-MeO-PCP has been available for purchase online as a research chemical. [7] It has been found in drug samples in the United Kingdom and Italy. It is also known to be used in France, The Netherlands, Sweden, The United States, Spain, and the Czech Republic. [8] 3-MeO-PCP is usually taken orally or nasally, but can also be injected or smoked ...
3-HO-PCP acts as a high-affinity uncompetitive antagonist of the NMDA receptor via the dizocilpine (MK-801) site (K i = 30 nM).[1] [3] It has much higher affinity than PCP for this site (K i = 250 nM, for comparison; 8-fold difference). [3]